Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide

Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II.

Refined structure of human carbonic anhydrase II at 2.0 A resolution.

Thermodynamic optimisation in drug discovery: a case study using carbonic anhydrase inhibitors.

Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II

SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKG
GPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVD
VLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMV
DNWRPAQPLKNRQIKASFK

2.6 M ammonium sulfate, 0.3 M sodium chloride, 0.1 M Tris-HCl, pH 8.5, 5 mM 4-hydroxymercurybenzoate, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Crystal structure of hCA II in complex with the benzenesulfonamide

Crystal structure of the human carbonic anhydrase II in complex with N-hydroxy benzenesulfonamide

Protein-inhibitor complex, LYASE-LYASE INHIBITOR complex