Structure of reovirus attachment protein sigma1 in complex with alpha-2,6-sialyllactose

beta-D-galactose; D-galactose; galactose

N-acetylneuraminic acid; sialic acid; alpha-sialic acid; O-SIALIC ACID

Crystal structure of reovirus attachment protein sigma1 in complex with sialylated oligosaccharides

N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose

Sigma1, Cell attachment protein, Hemagglutinin

QIEDKIEEILSKIYHIENEIARIKKLIGEGSGRPVLNQGVTSAGAPLSIRNNRMTMGLNDGLTLSGNNLAIRLPGNTGLN
IQNGGLQFRFNTDQFQIVNNNLTLKTTVFDSINSRIGAIEQSYVASAVTPLRLNSSTKVLDMLIDSSTLEINSSGQLTVR
STSPNLRYPIADVSGGIGMSPNYRFRQSMWIGIVSYSGSGLNWRVQVNSDIFIVDDYIHICLPAFDGFSIADGGDLSLNF
VTGLLPPLLTGDTEPAFHNDVVTYGAQTVAIGLSSGGTPQYMSKNLWVEQWQDGVLRLRVEGGGSITHSNSKWPAMTVSY
PRSFT

15% PEG200, 0.1M MES, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K

Reovirus sigma1 head domain at high resolution

Reovirus sigma1 head domain and parts of the tail

Reovirus sigma1 head domain in complex with its receptor junctional adhesion molecule-A.

Reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose

Reovirus attachment protein sigma1 in complex with alpha-2,8-disialyllactose

triple beta-spiral, beta-barrel, beta-spiral repeat, greek key motif, trimer, Viral attachment protein, sialic acid receptor Junctional adhesion molecule A, Viral capsid, VIRAL PROTEIN

VTSAGAPLSIRNNRMTMGLNDGLTLSGNNLAIRLPGNTGLNIQNGGLQFRFNTDQFQIVNNNLTLKTTVFDSINSRIGAT
EQSYVASAVTPLRLNSSTKVLDMLIDSSTLEINSSGQLTVRSTSPNLRYPIADVSGGIGMSPNYRFRQSMWIGIVSYSGS
GLNWRVQVNSDIFIVDDYIHICLPAFDGFSIADGGDLSLNFVTGLLPPLLTGDTEPAFHNDVVTYGAQTVAIGLSSGGAP
QYMSKNLWVEQWQDGVLRLRVEGGGSITHSNSKWPAMTVSYPRSFT