Crystal structure of geranylgeranyl pyrophosphate synthase from bacteroides thetaiotaomicron

New York SGX Research Center for Structural Genomics (NYSGXRC)

Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.

MSLDSISLIKTPIEAELEDFKALFDTPLSDSNALLDSVITHIRKRNGKMMRPILVLLVARLYGAVTPATLHAAVSLELLH
TASLVHDDVVDESTERRGQLSVNAIFNNKVSVLAGDYLLATSLVHAEQTNNYEIIRLVSSLGQKLAEGELLQLSNVSNHS
FSEEVYFDVIRKKTAALFAACAEAAALSVQVGEEEVAFARLLGEYIGICFQIKDDIFDYFDSKKIGKPTGNDMLEGKLTL
PALYALNTTKDAWAEQIAFKVKEGTATPDEIVRLIEFTKDNGGIEYACRTIEQYKKKAFDLLAALPDSNICLALRTYLDY
VVAREKEGHHHHHH

0.15M MALIC ACID, PH 7.0, 30% PEG 3350, 10% GLYCEROL, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 294K

New York SGX Research Center for Structural Genomics

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, ISOPRENE BIOSYNTHESIS, TRANSFERASE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ENZYME FUNCTION INITIATIVE, EFI, PSI-2

DSISLIKTPIEAELEDFKALFDTPLSDSNALLDSVITHIRKRNGKMMRPILVLLVARLYGAVTPATLHAAVSLELLHTAS
LVHDDVVDESTERRGQLSVNAIFNNKVSVLAGDYLLATSLVHAEQTNNYEIIRLVSSLGQKLAEGELLQLSNVSNHSFSE
EVYFDVIRKKTAALFAACAEAAALSVQVGEEEVAFARLLGEYIGICFQIKDDIFDYFDSKKIGKPTGNDMLEGKLTLPAL
YALNTTKDAWAEQIAFKVKEGTATPDEIVRLIEFTKDNGGIEYACRTIEQYKKKAFDLLAALPDSNICLALRTYLDYVVA
REK