Alternatingly modified 2'Fluoro RNA octamer f/rC4G4
2'-deoxy-2'-fluorocytidine 5'-(dihydrogen phosphate)
2'-deoxy-2'-fluoroguanosine 5'-(dihydrogen phosphate)
Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.
Sodium cacodylate (40 mM, pH 6.0), sodium chloride (80 mM), spermine tetrahydrochloride (12 mM), and 2-methyl-2,4-pentanediol (MPD; 10% (v/v)), equilibrated against a reservoir of MPD (1 mL, 35%), VAPOR DIFFUSION, HANGING DROP, temperature 291K
Chemically synthesized modified RNA octamer
RNA, 2'-FLUORO-RNA, O2'-MODIFICATION, OCTAMER, 2'-fluoro 2'-deoxycytidine, 2'-fluoro 2'-deoxyguanosine, siRNA