cIAP1-BIR3 domain in complex with the Smac-mimetic compound Smac066

Recognition of Smac-mimetic compounds by the BIR3 domain of cIAP1

LIGAND BMB D 600 HAS HIGH REAL SPACE R VALUE.

Baculoviral IAP repeat-containing protein 2
Repeat 3 (BIR3) domain, UNP residues 251-363

Inhibitor of apoptosis protein 2, IAP-2, hIAP-2, hIAP2, C-IAP1, TNFR2-TRAF-signaling complex protein 2, IAP homolog B, RING finger protein 48

MENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKW
FPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSLEHHHHHH

25% PEG 400, 0.1M Sodium Citrate, 0.1M Tris, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K

cIAP1-BIR3 domain in complex with the Smac-mimetic compound Smac037

Zinc-finger, Caspases, APOPTOSIS INHIBITOR

ENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWF
PRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTS