The Crystal Structure of Spot14, a modulator of lipogenesis
Crystal structure of Spot 14, a modulator of fatty acid synthesis.
sagittally focused Si 111 + sagittally focused Si 220
Thyroid hormone-inducible hepatic protein, SPOT14, S14
GS(MSE)QVLTKRYPKNCLLTV(MSE)DRYSAVVRN(MSE)EQVV(MSE)IPSLLRDVQLSGPGGSVQDGAPDLYTYFT (MSE)LKSICVEVDHGLLPREEWQAKVAGNETSEAENDAAETEEAEEDRISEELDLEAQFHLHFCSLHHILTHLTRKAQE VTRKYQE(MSE)TGQVL
GSMQVLTKRYPKNCLLTVMDRYSAVVRNMEQVVMIPSLLRDVQLSGPGGSVQDGAPDLYTYFTMLKSICVEVDHGLLPRE EWQAKVAGNETSEAENDAAETEEAEEDRISEELDLEAQFHLHFCSLHHILTHLTRKAQEVTRKYQEMTGQVL
0.100 M MES pH 6.0, 0.015 M magnesium chloride, 5% (w/v) polyethylene glycol 3000 and 30% (v/v) polyethylene glycol 200, VAPOR DIFFUSION, HANGING DROP, temperature 294K
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
alpha-helical, helical bundle, unknown function
MQVLTKRYPKNCLLTVMDRYSAVVRNMEQVVMIPSLLRDVQLSGPGGSVQDGAPDLYTYFTMLKSICVEVDHGLLPREEW QAKVAGNETSEAENDAAETEEAEEDRISEELDLEAQFHLHFCSLHHILTHLTRKAQEVTRKYQEMTGQVL