Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
100mM Tris pH 7.4, 25% MPD, vapor diffusion, hanging drop, temperature 298K
MMHFGN hexapeptide (residues 138-143) from golden hamster prion protein
MIHFGN hexapeptide (residues 137-142) from mouse prion protein
MIHFGND (residues 137-143) from mouse prion protein
IIHFGS (UNP residues 138-143) from human prion
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
amyloid-like protofibril, PROTEIN FIBRIL