Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) with NMP

Histone recognition and large-scale structural analysis of the human bromodomain family.

hPB1, Polybromo-1D, BRG1-associated factor 180, BAF180

SMSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDID
SMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGD

0.15M NaNO3
25% PEG 3350
10% Ethylene Glycol, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES: WITH TLS ADDED

PB1, polybromo 1 isoform 1, BAF180, Polybromo-1D, PBRM1, BRG1-associated factor 180, Structural Genomics Consortium, SGC, Bromodomain, Chromatin regulator, DNA-binding, Nucleus, Phosphoprotein, Transcription, Transcription regulation

SGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSM
VEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGD