1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP

Center for Structural Genomics of Infectious Diseases (CSGID)

MHHHHHHSSGVDLGTENLYFQSNAMNAKFIVIEGLEGAGKSTAIQVVVETLQQNGIDHITRTREPGGTLLAEKLRALVKE
EHPGEELQDITELLLVYAARVQLVENVIKPALARGEWVVGDRHDMSSQAYQGGGRQIAPSTMQSLKQTALGDFKPDLTLY
LDIDPKLGLERARGRGELDRIEKMDISFFERARERYLELANSDDSVVMIDAAQSIEQVTADIRRALQDWLSQVNRV

7mg/mL protein; The PACT Suite condition #47 (D11), pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 295K

Center for Structural Genomics of Infectious Diseases

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Thymidylate Kinase, Vibrio cholerae, Structural Genomics, Infectious Diseases, Center for Structural Genomics of Infectious Diseases, ATP-binding, Kinase, Nucleotide biosynthesis, Nucleotide-binding, Transferase, CSGID

MNAKFIVIEGLEGAGKSTAIQVVVETLQQNGIDHITRTREPGGTLLAEKLRALVKEEHPGEELQDITELLLVYAARVQLV
ENVIKPALARGEWVVGDRHDMSSQAYQGGGRQIAPSTMQSLKQTALGDFKPDLTLYLDIDPKLGLERARGRGELDRIEKM
DISFFERARERYLELANSDDSVVMIDAAQSIEQVTADIRRALQDWLSQVNRV