Crystal Structure of the PAS domain of Rv1364c
Role of a PAS sensor domain in the Mycobacterium tuberculosis transcription regulator Rv1364c
(MSE)GSSHHHHHHSSGLVPRGSHAS(MSE)AAE(MSE)DWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYR GFSPLLDTVGQPAREVYPELEGQQIYE(MSE)LDRVYQTGEPQSGSEWRLQTDYDGSGVEERYFDFVVTPRRRADGSIEG VQLIVDDVTSRVRARQAAEARVEELSERYRNVRDSATV(MSE)QQ
MGSSHHHHHHSSGLVPRGSHASMAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYRGFSPLLDTVGQP AREVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDYDGSGVEERYFDFVVTPRRRADGSIEGVQLIVDDVTSRVRARQ AAEARVEELSERYRNVRDSATVMQQ
2.5M ammonium sulphate, 5% Isopropanol, .1M tris-chloride, pH 8, Under oil, temperature 300K
PAS domain, Rv1364c, Sensory domain, Mycobacteium tuberculosis, Small molecule binding domain, SIGNALING PROTEIN
MAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYRGFSPLLDTVGQPAREVYPELEGQQIYEMLDRVYQ TGEPQSGSEWRLQTDYDGSGVEERYFDFVVTPRRRADGSIEGVQLIVDDVTSRVRARQAAEARVEELSERYRNVRDSATV MQQ