M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA

Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin

GLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGVVLDEVIFSKHKGDTKMSAEDKALFRRCAAD
YASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFACQ
TFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTRMMIGRFCAQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVD
YSAFDANHCSDAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVEGGIPSGCSATSIINTILNNIYVLYALR
RHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYK
PVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDAAALEHH

30% PEG 4000, 0.1M HEPES pH 7.0, 4% butyrolactone, 0.2M Magnesium acetate, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Foot and Mouth Disease Virus RNA-dependent RNA polymerase

Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA

Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein

Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein

Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP

Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP

M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA

G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, tetragonal structure

G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure

M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

RNA dependent RNA polymerase, 3d polymerase, foot-and-mouth disease virus, ribavirin, Transferase-RNA complex

GLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGVVLDEVIFSKHKGDTKMSAEDKALFRRCAAD
YASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFACQ
TFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTRMMIGRFCAQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVD
YSAFDANHCSDAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVEGGMPSGCSATSIINTILNNIYVLYALR
RHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYK
PVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDA