Unified assembly mechanism of ASC-dependent inflammasomes

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes.

over holes in lacey carbon grids, no support

Plunged into liquid ethane (FEI VITROBOT MARK IV)

Apoptosis-associated speck-like protein containing a CARD

hASC, Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1

MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTANVLRDMGLQE
MAGQLQAATHQ

helical polymer, variable twist, death domain, APOPTOSIS