Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPBTB/3-box

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.

GSGGSGGQNT(MSE)N(MSE)VKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSA(MSE)FEHE
(MSE)EESKKNRVEINDVEPEVFKE(MSE)(MSE)CFIYTGKAPNLDK(MSE)ADDLLAAADKYALERLKV(MSE)CEDA
LCSNLSVENAAEILILADLHSADQLKTQAVDFINYHATDVLETSG

GSGGSGGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEIND
VEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFI
NYHATDVLETSG

BTB, SPOP, ubiquitin, ligase, Nucleus, Ubl conjugation pathway, PROTEIN BINDING

GQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVF
KEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA