Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.

Nucleoporin CDC31, Nuclear pore protein CDC31

Leucine permease transcriptional regulator

MSKNRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDD
FYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTD
S

MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRET
VLKQIREFLEEIVDTQ

0.1M MES pH6.5, 16% PEG4K, 20% glycerol - see publication for complete details, VAPOR DIFFUSION, HANGING DROP, temperature 291K

P21 crystal structure obtained as described in publication

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Sac3:Cdc31:Sus1 component of TREX-2 complex

gene gating, complex, Cell cycle, Cell division, Mitosis, mRNA transport, Nuclear pore complex, Nucleus, Phosphoprotein, Protein transport, Translocation, Transport, Transcription, Transcription regulation