Crystal structure of Intern Domain of proteasome-associated ATPase, Mycobacterium tuberculosis

Structural Insights on the Mycobacterium tuberculosis Proteasomal ATPase Mpa.

MPSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIDAASLKKGQTVRLNEALTVVEAGTFEAVGEISTLREILADGHRALV
VGHADEERVVWLADPLIAEDLPDGLPEALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEELVPR

20% PEG2000, 50 mM MgCl2, 50 mM NaCl, 0.1M MES, C-HEGA, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 294K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

the biological assembly is a hexamer, which is composed of six monomer of Inter-Domain and contained in the asymmetric unit, two biological hexamer form crystal packing.

five strand beta barrel, hexamer, ATP-binding, Nucleotide-binding, HYDROLASE, AAA ATPase, Proteasomal ATPase

PSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIDAASLKKGQTVRLNEALTVVEAGTFEAVGEISTLREILADGHRALVV
GHADEERVVWLADPLIAEDLPDGLPEALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEE