Crystal structure of F85W mutant of Human acidic fibroblast growth factor

The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.

HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta

HHHHHHFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLY
GSQTPNEECLWLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

3M Na-formate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K

HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG

CRYSTAL STRUCTURE OF L44F/C83T/C117V/F132W MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF C117I MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF F132W MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF V31I MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF L44W MUTANT OF HHUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF L44F/F132W MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF C83S MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF C83T MUTANT OF HHUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF C83A MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF K12V/C83I/C117V MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF C83V MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

CRYSTAL STRUCTURE OF A66C MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR

beta-trefoil, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE

FNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPN
EECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD