A new form of DNA-drug interaction in the minor groove of a coiled coil
Coiled-coil conformation of a pentamidine-DNA complex
20 mM MgCl2, 50 mM MES, 15% Isopropanol, 3.62 mM ds-DNA, 16.86 mM PNT, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 278.15K
Synthesized by using phosphoramiditine method
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
DNA drug pentamidine coiled-coil all-AT, DNA