Crystal structure of human type III collagen G982-G1023 containing C-terminal cystine knot
Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries.
30% PEG 550, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Chemically synthesized peptide G982-G1023 based on the fragment 1158-1199 of the human Collagen alpha-1(III) chain, CO3A1_HUMAN, UniProt entry P02461.
The peptide assembles into a triple helix (3 chains of the 42-mer)
collagen III, cystine knot, triple helix, glycine, MAD phasing, Alternative splicing, Disease mutation, Ehlers-Danlos syndrome, Extracellular matrix, Glycoprotein, Hydroxylation, Phosphoprotein, Polymorphism, Secreted, Structural protein