Tetragonal crystal structure of Tas3 C-terminal alpha motif

An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.

RNA-induced transcriptional silencing complex protein tas3

GSHMNPLASLTTDKNDLYINWLKSLSFFQTNSSCAEALVKVIPHYHNKLIDFSQVLQLVFSASEKFPIQENQPLPEQLMF
LSNLEKQTPFAKAVGSSIYKLVTGKNLSLDFASQILKEASILEH

12% PEG4000, 0.1 M Tris 7.5, 0.2 M KCl and 50 mM MgCl2, VAPOR DIFFUSION, HANGING DROP, temperature 293K

The same protein of hexagonal crystal form

all alpha motif, RITS complex, immunoglobulin fold, Cell cycle, Chromosome partition, Nucleus, RNA-mediated gene silencing, NUCLEAR PROTEIN

NPLASLTTDKNDLYINWLKSLSFFQTNSSCAEALVKVIPHYHNKLIDFSQVLQLVFSASEKFPIQENQPLPEQLMFLSNL
EKQTPFAKAVGSSIYKLVTGKNLSLDFASQILKEASILEH