X-ray structure of the aquaglyceroporin from Plasmodium falciparum

Center for Structures of Membrane Proteins (CSMP)

Beta-Octylglucoside; octyl beta-D-glucoside; octyl D-glucoside; octyl glucoside

Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum.

MHMLFYKSYVREFIGEFLGTFVLMFLGEGATANFHTTGLSGDWYKLCLGWGLAVFFGILVSAKLSGAHLNLAVSIGLSSI
NKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENI
CGKFHILKLSSVVGLIILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVFCQFYDK
VICPLVDLANNEKDGVDL

17% PEG MME 2000, 0.1M Sodium citrate, 15% Glycerol, 0.04M n-octyl-B-D-glucopyranoside, 0.01 Nickel sulfate, 0.01M DTT, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 291K

Center for Structures of Membrane Proteins

Crystal structure of aquaglyceroporin from E. coli in complex with substrate glycerol

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Membrane protein, glycerol, water, transport, Structural Genomics, PSI-2, Protein Structure Initiative, Center for Structures of Membrane Proteins, CSMP, Porin, Transmembrane