Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor

Numb-binding protein 1, Ligand of Numb-protein X 1

MHHHHHHSSGVDLGTENLYFQSMHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLN
VDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEGSIV

1.53M Potassium phosphate, 0.27M Sodium phosphate, 1% PEG 3350, pH 7.4, VAPOR DIFFUSION, SITTING DROP, temperature 293K

Synapse associated protein 97 PDZ2 domain variant C378G with C-terminal GluR-A peptide

SEQUENCE
This is a C-terminal peptide from the coxsackievirus
and adenovirus receptor.

PDB entries 2AWW, 2BYG, 2AWX, 2AWU, 2G2L

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

PDZ, bound ligand, Structural Genomics, Structural Genomics Consortium, SGC, Ligase, Metal-binding, Ubl conjugation pathway, Zinc-finger, UNKNOWN FUNCTION

HEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSS
SIVLKALEVKE