Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis in complex with arginine

TB Structural Genomics Consortium (TBSGC)

Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.

20% PEG 10000, 0.1 M Tris-HCl, 0.1 M Guanidine-HCl, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K

Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

AUTHORS STATE THAT THE ASYMMETRIC UNIT CONTAINS ONE HEXAMER THAT IS A DIMER OF TRIMERS. EITHER HEXAMER OR TRIMER MIGHT BE THE BIOLOGICAL UNIT.

L-ARGININE REPRESSOR, DNA BINDING PROTEIN, CORE, OLIGOMERIZATION DOMAIN, ALPHA/BETA TOPOLOGY, Structural Genomics, TB Structural Genomics Consortium, TBSGC, Amino-acid biosynthesis, Arginine biosynthesis, DNA-binding, Transcription, Transcription regulation, PSI-2, Protein Structure Initiative