Ligand Migration and Binding in The Dimeric Hemoglobin of Scapharca Inaequivalvis: I25W with CO Bound to HEME and in the Presence of 3 Atoms of XE

Ligand Migration and Binding in the Dimeric Hemoglobin of Scapharca inaequivalvis

PSVYDAAAQLTADVKKDLRDSWKVWGSDKKGNGVALMTTLFADNQETIGYFKRLGDVSQGMANDKLRGHSITLMYALQNF
IDQLDNPDDLVCVVEKFAVNHITRKISAAEFGKINGPIKKVLASKNFGDKYANAWAKLVAVVQAAL

1.5-2.5M PHOSPHATE BUFFER, pH 7.50, SMALL TUBES, temperature 298K

mutant(H69V/I114M) of HBI in complex with CO

THE MODEL WAS REFINED WITH A COMBINATION OF CNS AND SHELX WITH A ROUND OF MANUAL INTERVENTION IN BETWEEN.

OXYGEN TRANSPORT, ALLOSTERY, OXYGEN AFFINITY, Cytoplasm, Heme, Iron, Metal-binding, OXYGEN STORAGE/TRANSPORT, OXYGEN BINDING

PSVYDAAAQLTADVKKDLRDSWKVIGSDKKGNGVALMTTLFADNQETIGYFKRLGDVSQGMANDKLRGHSITLMYALQNF
IDQLDNPDDLVCVVEKFAVNHITRKISAAEFGKINGPIKKVLASKNFGDKYANAWAKLVAVVQAAL