Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2

Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V.

NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGEIVSETSDSFTFKTVDGQDRQVKKDDANQRN
PIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDV
AYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQANGSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGK
FIEIQFNSAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDS
EEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAG
RDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQF
FNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEP
RFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASL
MATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNAVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQK
ATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEARE

TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MG-PYROPHOSPHATE

DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH N-METHYL-O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE.

MYOSIN II DICTYOSTELIUM DISCOIDEUM MOTOR DOMAIN S456E BOUND WITH MGADP-ALF4

COMPLEX BETWEEN DICTYOSTELIUM MYOSIN AND MGADP AND VANADATE AT 1.9A RESOLUTION

X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN

STRUCTURE OF THE NUCLEOTIDE-FREE MYOSIN II MOTOR DOMAINFROM DICTYOSTELIUM DISCOIDEUM FUSED TO THE GTPASE DOMAINOF DYNAMIN 1 FROM RATTUS NORVEGICUS

CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP-METAVANADATE AND PENTABROMOPSEUDILIN

MYOSIN II DICTYOSTELIUM DISCOIDEUM MOTOR DOMAIN S456Y BOUND WITH MGADP-ALF4

CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP-METAVANADATE AND PENTACHLOROCARBAZOLE

CRYSTAL STRUCTURE OF THE APO MOTOR DOMAIN OF DICTYOSTELLIUMMYOSIN II

CRYSTAL STRUCTURE OF MYOSIN-2 IN COMPLEX WITH TRIBROMODICHLOROPSEUDILIN

MYOSIN II DICTYOSTELIUM DISCOIDEUM MOTOR DOMAIN S456Y BOUND WITH MGADP-BEFX

DICTYOSTELIUM DISCOIDEUM MYOSIN II MOTOR DOMAIN S456E WITH BOUND MGADP-BEFX

TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-ALF4

CRYSTAL STRUCTURE OF THE NUCLEOTIDE-FREE DYNAMIN A GTPASEDOMAIN, DETERMINED AS MYOSIN FUSION

STRUCTURE OF THE NUCLEOTIDE-FREE MYOSIN II MOTOR DOMAINFROM DICTYOSTELIUM DISCOIDEUM

DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM FLUORIDE.

MOLECULAR MECHANISM OF PENTACHLOROPSEUDILIN MEDIATED INHIBITION OF MYOSIN MOTOR ACTIVITY

CRYSTAL STRUCTURE OF MYOSIN-2 IN COMPLEX WITH ADP- METAVANADATE

X-RAY CRYSTAL STRUCTURE OF THE MG (DOT) 2'(3')-O -(N-METHYLANTHRANILOYL) NUCLEOTIDE BOUND TO DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN

CRYSTAL STRUCTURE OF THE DYNAMIN A GTPASE DOMAIN COMPLEXEDWITH GDP, DETERMINED AS MYOSIN FUSION

THE STRUCTURAL BASIS OF BLEBBISTATIN INHIBITION ANDSPECIFICITY FOR MYOSIN II

CRYSTAL STRUCTURE OF THE MGATP COMPLEX FOR THE MOTOR DOMAINOF DICTYOSTELIUM MYOSIN II

DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH M-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE.

DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH O,P-DINITROPHENYL AMINOPROPYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE.

STRUCTURE OF A GENETICALLY ENGINEERED MOLECULAR MOTOR

DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH O,P-DINITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE.

DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH P-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE.

TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3

ENGINEERED RESIDUE IN CHAIN X, GLY 680 TO ALA