NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE

The Crystal Structure of the Y140F Mutant of Adp-L-Glycero-D-Manno-Heptose 6-Epimerase Bound to Adp-Beta-D-Mannose Suggests a One Base Mechanism.

AGME, ADP-L-GLYCERO-BETA-D-MANNO-HEPTOSE-6-EPIMERASE, ADP-GLYCEROMANNO-HEPTOSE 6-EPIMERASE, ADP-HEP 6-EPIMERASE

MHHHHHHSSGLVPRGSGMKETAAAKFERQHMDSPDLGTGGGSGIEGRMIIVTGGAGFIGSNIVKALNDKGITDILVVDNL
KDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLY
ASSAATYGGRTSDFIESREYEKPLNVFGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLN
NGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQ
AFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA

ENGINEERED RESIDUE IN CHAIN A, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN B, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN C, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN D, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN E, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN F, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN G, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN H, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN I, TYR 140 TO PHE ENGINEERED RESIDUE IN CHAIN J, TYR 140 TO PHE

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. ATOM RECORD CONTAINS RESIDUAL B FACTORS ONLY
ISOMERASE, CARBOHYDRATE METABOLISM, STRESS RESPONSE