Critical structural role for the PH and C1 domains of the Vav1 exchange factor

Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor.

RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1

P21-RAC1, RAS- LIKE PROTEIN TC25, CELL MIGRATION-INDUCING GENE 5 PROTEIN, RAC1

MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLI
CFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL
TQRGLKTVFDEAIRAVLCPPPVKK

GDEIYEDLMRLESVPTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTH
FLKELKDALAGPGATTLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVP
MQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGEL
KITSVERRSKTDRYAFLLDKALLICKRRGDSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTR
ELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVPPCGRHGQ
DFAGTM

CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITHARFAPTIN (P21)

CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINENUCLEOTIDE EXCHANGE REGION OF TIAM1

CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITHARFAPTIN (P41)

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE GAP DOMAIN OF THE PSEUDOMONAS AERUGINOSA EXOS TOXIN AND HUMAN RAC

ALTERNATIVE SPLICING OF RAC1 GENERATES RAC1B , A SELF-ACTIVATING GTPASE

SOLUTION STRUCTURE OF N-TERMINAL SH3 DOMAIN MUTANT(P33G) OFMURINE VAV

RAC1-RHOGDI COMPLEX INVOLVED IN NADPH OXIDASE ACTIVATION

CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASEAND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1

ACTIVATED RAC1 BOUND TO ITS EFFECTOR PHOSPHOLIPASE C BETA 2

NMR STRUCTURE OF THE Y174 AUTOINHIBITED DBL HOMOLGY DOMAIN

CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITHARFAPTIN

CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.

RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, PROTO-ONCOGENE VAV

LIPOPROTEIN, GTP-BINDING, METAL-BINDING, PROTO-ONCOGENE, PHOSPHOPROTEIN, EXCHANGE FACTOR, RAC, VAV, GTPASE, MEMBRANE, SH2 DOMAIN, SH3 DOMAIN, METHYLATION, ZINC-FINGER, PRENYLATION, GUANINE-NUCLEOTIDE RELEASING FACTOR, PHORBOL-ESTER BINDING, ADP-RIBOSYLATION, NUCLEOTIDE-BINDING, SIGNALING PROTEIN