X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC)

X-Ray Structure of a Prokaryotic Pentameric Ligand-Gated Ion Channel

APADNAADARPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFIN
VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEW
WIRKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLT
VVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIRGIT
L

PHASES WERE EXTENDED BY CYCLIC 10-FOLD NCS AVERAGING

15 % PEG 4000, 200MM AMMONIUM SULFATE, 50 MM ADA PH 6.5

SHEET
THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN
ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW,
TWO SHEETS ARE DEFINED.

TIGHT NCS POSITIONAL AND B-FACTOR RESTRAINTS
PENTAMERIC LIGAND GATED ION CHANNEL, MEMBRANE PROTEIN, PROKARYOTIC CYS-LOOP RECEPTOR, CATION SELECTIVE CHANNEL

APADNAADARPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFIN
VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEW
WIRKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLT
VVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQAMGVEDDLLIQRCRLAFPLGFLAIGCVLVIRGIT
L