SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal.
Crystal Structure at 1.92 A Resolution of the RNA-Binding Domain of the U1A Spliceosomal Protein Complexed with an RNA Hairpin
Resonance Assignments and Solution Structure of the Second RNA-Binding Domain of Sex-Lethal Determined by Multidimensional Heteronuclear Magnetic Resonance
Determination of the Secondary Structure and Folding Topology of an RNA Binding Domain of Mammalian Hnrnp A1 Protein Using Three-Dimensional Heteronuclear Magnetic Resonance Spectroscopy
1H, 13C, and 15N NMR Assignments and Global Folding Pattern of the RNA-Binding Domain of the Human Hnrnp C Proteins
Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A
RNA-BINDING DOMAIN 1 (RBD1), RESIDUES 122 - 209
ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYA RPGGESIK
RIKEN Structural Genomics/Proteomics Initiative
REFINEMENT WAS DONE USING THE HYBRID DISTANCE GEOMETRY/SIMULATED ANNEALING METHOD (NILGES, M., CLORE, G.M., & GRONENBORN, A.M. (1988) FEBS LETT 229, 317-324) AS CONTAINED IN X-PLOR PROGRAM VERSION 3.1 (BRUNGER, 1992). THE RMSD FOR THE BACKBONE COORDINATES OF THE 20 STRUCTURES ACCEPTED AFTER THE LAST ROUND OF REFINEMENT COMPARED TO THE AVERAGE COORDINATES WAS 0.86 (FOR RESIDUES INVOLVED IN SECONDARY STRUCTURE).
HYBRID DISTANCE GEOMETRY/ SIMULATED ANNEALING METHOD
RNA-BINDING DOMAIN, ALTERNATIVE SPLICING, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Structural Genomics
MYGNNNPGSNNNNGGYPPYGYNNKSSGGRGFGMSHSLPSGMSRYAFSPQDTEFSFPSSSSRRGYNDFPGCGGSGGNGGSA NNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDY KTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQK NILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPANVPPPPPQPPA HMAAAFNMMHRGRSIKSQQRFQNSHPYFDAKKFI