Solution structure of calponin homology domain of IQGAP1
NMR structure of the calponin homology domain of human IQGAP1 and its implications for the actin recognition mode.
GPLGSLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQ TRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEE EINNMKTELEKYGIQMPAFSKIGGILANEL
0.90 mM [U-99% 13C; U-99% 15N] CH domain-1, 20 mM sodium phosphate-2, 150 mM sodium chloride-3, 1 mM DTT-4, 1 mM sodium azide-5, 90% H2O/10% D2O
0.90 mM [U-99% 13C; U-99% 15N] CH domain-6, 20 mM sodium phosphate-7, 150 mM sodium chloride-8, 1 mM DTT-9, 1 mM sodium azide-10, 100% D2O
0.90 mM [U-99% 15N] CH domain-11, 20 mM sodium phosphate-12, 150 mM sodium chloride-13, 1 mM DTT-14, 1 mM sodium azide-15, 90% H2O/10% D2O
F-actin binding protein, PROTEIN BINDING
LTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKA TGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNM KTELEKYGIQMPAFSKIGGILANEL