Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 12-30), orthorhombic form I

L3MBTL1 recognition of mono- and dimethylated histones.

Lethal(3)malignant brain tumor-like protein

L(3)mbt-like, L(3)mbt protein homolog, H-l(3)mbt protein, H-L(3)MBT, L3MBTL1

GEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECH
DFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNP
SLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTW
AFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLG
PREPSSASPGG

5% PEG 4000, 0.1M Sodium acetate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 300K

Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), trigonal form

Crystal structure of L3MBTL1 protein in complex with MES

Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), orthorhombic form II

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

L(3)MBT-LIKE PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSCRIPTION, Chromatin regulator, DNA-binding, Metal-binding, Nucleus, Repressor, Transcription regulation, Zinc-finger, Chromosomal protein, Methylation, Nucleosome core