The crystal structure of isomerase domain of glucosamine-6-phosphate synthase from Candida albicans

BETA-D-GLUCOSE-6-PHOSPHATE; 6-O-phosphono-beta-D-glucose; 6-O-phosphono-D-glucose; 6-O-phosphono-glucose

The Crystal and Solution Studies of Glucosamine-6-phosphate Synthase from Candida albicans

BG6 A 713 HAS WRONG CHIRALITY AT ATOM C1

BG6 B 713 HAS WRONG CHIRALITY AT ATOM C1

BG6 C 713 HAS WRONG CHIRALITY AT ATOM C1

BG6 D 713 HAS WRONG CHIRALITY AT ATOM C1

isomerase domain of glutamine-fructose-6-phosphate transaminase (isomerizing)

Hexosephosphate aminotransferase; D-fructose-6- phosphate amidotransferase; GFAT

MKGPYKHFMQKEIFEQPDSAFNTMRGRIDFENCVVTLGGLKSWLSTIRRCRRIIMIACGTSYHSCLATRSIFEELTEIPV
SVELASDFLDRRSPVFRDDTCVFVSQSGETADSILALQYCLERGALTVGIVNSVGSSMSRQTHCGVHINAGPEIGVASTK
AYTSQYIALVMFALSLSNDSISRKGRHEEIIKGLQKIPEQIKQVLKLENKIKDLCNSSLNDQKSLLLLGRGYQFATALEG
ALKIKEISYMHSEGVLAGELKHGILALVDEDLPIIAFATRDSLFPKVMSAIEQVTARDGRPIVICNEGDAIISNDKVHTT
LEVPETVDCLQGLLNVIPLQLISYWLAVNRGIDVDFPRNLAKSVTVE

0.2 M magnesium acetate, 0.1 M sodium cacodylate pH 6.5, 30 % v/v 2-methyl-2,4-pentanediol; 10-fold excess of UDP-GlcNAc and Glc-6-P;, VAPOR DIFFUSION, HANGING DROP, temperature 277K

The same protein complexed with Fru-6-P and UDP-GlcNAc

The same protein complexed with 2-amino-2-deoxy-D-mannitol 6-phosphate and UDP-GlcNAc

The asymmetric unit contains the tetrameric biological assembly

glucosamine-6-phosphate synthase; aldose/ketose isomerase; crystal structure; Rossmann-like fold;, TRANSFERASE