VEALYL peptide derived from human insulin chain B, residues 12-17
Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
2mM peptide in 100 mM NaCl and 50 mM phosphate. Crystals can be more easily reproduced by dissolving peptide to 2 mM in water at room temperature, pH 2.5, VAPOR DIFFUSION, HANGING DROP, temperature 310K
polyalanine beta strands with ideal geometry
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
A steric zipper can be generated by repeated unit cell translations of the asymmetric unit along the b axis.
steric zipper, anti-parallel beta-sheet, PROTEIN FIBRIL