Crystal structure of AVR4 (R112L/C122S)-BNA complex

5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE

Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.

Chirality errors at CB centers of THR 61,261,278.

ARKCSLTGKWTNNLGSIMTIRAVNSRGEFTGTYLTAVADNPGNITLSPLLGIQHKRASQPTFGFTVHWNFSESTTVFTGQ
CFIDRNGKEVLKTMWLLRSSVNDISYDWKATLVGYNNFTRLSTVEE

1.5-1.9M NaFormate, 0.1M Acetate, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

The second part of the biological assembly is generated by the two fold axis: Y+1, -X+1, -Z+0.5

avidin, styreptavidin, AVR4, high affinity, pseudo catalysis, LIGAND BINDING PROTEIN

ARKCSLTGKWTNNLGSIMTIRAVNSRGEFTGTYLTAVADNPGNITLSPLLGIQHKRASQPTFGFTVHWNFSESTTVFTGQ
CFIDRNGKEVLKTMWLLRSSVNDISYDWKATRVGYNNFTRLCTVEE