Solution NMR Structure of Designed Protein DA05R1, Northeast Structural Genomics Consortium (NESG) Target OR690
Northeast Structural Genomics Consortium (NESG)
Design of structurally distinct proteins using strategies inspired by evolution.
ADENIAKFEKAYKKAEELNQGELMGRALYNIGLEKNKMGKAREAAEYFFRAAIVFYKEHDTDGLRRAAKSLKEAITAIPE EEGRKEAKEMAKKAEEWLQAEQNN
Northeast Structural Genomics Consortium
660 uM [U-5% 13C; U-15N] DA05R, 25 mM sodium phosphate, 50 mM sodium chloride, 0.02 % sodium azide, 1 mM protein inhibitor cocktail, 50 uM DSS, 90% H2O/10% D2O
1 mM [U-13C; U-15N] DA05R, 25 mM sodium phosphate, 50 mM sodium chloride, 0.02 % sodium azide, 1 mM protein inhibitor cocktail, 50 uM DSS, 90% H2O/10% D2O
Brunger, Adams, Clore, Gros, Nilges and Read
Zimmerman, Moseley, Kulikowski and Montelione
designed protein, DE NOVO PROTEIN, PSI-Biology, Structural Genomics, Northeast Structural Genomics Consortium, NESG