Solution structure of the FHA domain of TbPar42
Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.
GPMVTSTGLLSRVAAVEKAAEIAKPPPPKVVELTEAAKQLPQHIIGVTDPTKLNAQVSYFQCPPWAALPSVACHLQCTRD GLPLPALGLHRFPFYLFGRSKVCDYVLEHPSISSVHAVLVFHGGQRCFVLMDLGSTNGVKLNGNRIEKRRPLPAPVGSSI QFGFSSRVYKVQLGPPSSS
15N13C FHA domain in 50mM KPiBuffer+2mM DTT-1
15N FHA domain in 50mM KpiBuffer+2mM DTT-2
13C FHA domain in 50mM KpiBuffer+2mM DTT-3
torsion angle dynamics, simulated annealing, molecular dynamics
0.6 mM [U-13C; U-15N] 15N13C FHA domain in 50mM KPiBuffer+2mM DTT, 90% H2O/10% D2O
1 mM [U-15N] 15N FHA domain in 50mM KpiBuffer+2mM DTT, 90% H2O/10% D2O
0.6 mM [U-13C] 13C FHA domain in 50mM KpiBuffer+2mM DTT, 100% D2O
1 mM FHA domain in 50mM KPiBuffer+2mM DTT, 50 mMKPi Buffer + 2mM DTT
MVTSTGLLSRVAAVEKAAEIAKPPPPKVVELTEAAKQLPQHIIGVTDPTKLNAQVSYFQCPPWAALPSVACHLQCTRDGL PLPALGLHRFPFYLFGRSKVCDYVLEHPSISSVHAVLVFHGGQRCFVLMDLGSTNGVKLNGNRIEKRRPLPAPVGSSIQF GFSSRVYKVQLGPPSSS