Structure of complex of MDM2(3-109) and P73 TAD(10-25)
Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition
Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2
p53-like transcription factor, p53-related protein
NTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLL GDLFGVPSFSVKEHRKIYTMIYRNLVV
0.9 mM [U-99% 13C; U-99% 15N] E3 Ubiquitin-protein Ligase MDM2-1, 90% H2O/10% D2O
Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax
MDM2, P73 TAD, P53, LIGASE-PEPTIDE complex