Biosynthetic engineered B28K-B29P human insulin monomer structure in in water/acetonitrile solutions.
Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
torsion angle dynamics, DGSA-distance geometry simulated annealing
2.5 - 3.0 mM insulin, residues 90-110, 2.5 - 3.0 mM insulin, residues 25-54, 73 % H2O, 27 % CD3CN, H2O / CD3CN
2.5 - 3.0 mM insulin, residues 90-110, 2.5 - 3.0 mM insulin, residues 25-54, 73 % D2O-7, 27 % CD3CN-8, D2O / CD3CN
Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, and Kollman