A domain flip as a result of a single amino-acid substitution.
DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLT ISSLQAEDVAVYYCQQYYSTPYSFGQGTKLEIKR
IMMUNOGLOBULIN, KAPPA-IV, LIGHT CHAIN DIMER