Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4
The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.
Torsion angle dynamics followed by refinement by Cartesian dynamics in explicit water.
Brunger, Adams, Clore, Gros, Nilges and Read