Solution structure of human SDF1-alpha H25R
SDF-1, hSDF-1, C-X-C motif chemokine 12, Pre-B cell growth-stimulating factor, PBSF, hIRH, SDF-1-beta(3-72), SDF-1-alpha(3-67)
STRUCTURES ARE BASED ON A TOTAL OF 1430 NOE CONSTRAINTS (339 INTRA, 388 SEQUENTIAL, 263 MEDIUM, AND 440 LONG RANGE) AND 65 PHI AND PSI DIHEDRAL ANGLE CONSTRAINTS.
AUTOMATED METHODS WERE USED FOR BACKBONE CHEMICAL SHIFT ASSIGNMENT AND ITERATIVE NOE REFINEMENT. FINAL STRUCTURES WERE OBTAINED BY MOLECULAR DYNAMICS IN EXPLICIT SOLVENT
Eccles, C., Guntert, P., Billeter, M., Wuthrich, K.
chemokine, SDF1-alpha, Chemotaxis, Growth factor, CYTOKINE