Structure of an intramolecular G-quadruplex containing a G.C.G.C tetrad formed by human telomeric variant CTAGGG repeats
Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad
DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3')
(DA)(DG)(DG)(DG)(DC)(DT)(DA)(DG)(DG)(DG)(DC)(DT)(DA)(DG)(DG)(DG)(DC)(DT)(DA)(DG) (DG)(DG)
HUMAN TELOMERE DNA SOLUTION STRUCTURE IN THE PRESENCE OF NA
HUMAN TELOMERE DNA CRYSTAL STRUCTURE IN THE PRESENCE OF K
3 REPEATS OF HUMAN TELOMERE DNA SOLUTION STRUCTURE
END-MODIFIED HUMAN TELOMERE DNA CRYSTAL STRUCTURE IN THE PRESENCE OF K
HUMAN TELOMERE DNA SOLUTION STRUCTURE IN THE PRESENCE OF K CATIONS 16BRG FORM 1
HUMAN TELOMERE DNA SOLUTION STRUCTURE IN THE PRESENCE OF K CATIONS NATURAL FORM 1
HUMAN TELOMERE DNA SOLUTION STRUCTURE IN THE PRESENCE OF K CATIONS FORM 2 15BRG
STRUCTURE OF A TWO-G-TETRAD BASKET-TYPE INTRAMOLECULAR G-QUADRUPLEX FORMED BY HUMAN TELOMERIC REPEATS IN K+ SOLUTION (7BRG)
STRUCTURE OF A TWO-G-TETRAD BASKET-TYPE INTRAMOLECULAR G-QUADRUPLEX FORMED BY HUMAN TELOMERIC REPEATS IN K+ SOLUTION
back calculated data agree with experimental NOESY spectrum
DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3')-1
DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3')-2
DGSA-distance geometry simulated annealing, molecular dynamics, matrix relaxation
0.5-2.0mM DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3')-1, 70mM potassium chloride, 20mM potassium phosphate, 90% H2O/10% D2O
0.5-2.0mM DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3')-2, 70mM potassium chloride, 20mM potassium phosphate, 100% D2O
anticancer targets, CTAGGG repeat, G-quadruplex, human telomere instability, DNA