Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles
Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.
Amylin, Diabetes-associated peptide, DAP
structures with the least restraint violations
20 mM sodium phosphate, 0.02 % sodium azide, 120 mM sodium chloride, 10 % 99.9% D2O, 200 mM 98% deuterated DPC, 2.5 mM entity, 90% H2O/10% D2O
Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax
Schwieters, Kuszewski, Tjandra and Clore
IAPP, Amylin, Islet Amyloid Polypeptide, Rat IAPP, Amidation, Amyloid, Cleavage on pair of basic residues, Disulfide bond, Hormone, Secreted