Solution Structure of the R13 Domain of Talin
The structure of the C-terminal actin-binding domain of talin.
GIDPFTDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQ GKVGAIPANALDDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAM KRLQAAGNAVKRASDNLVKAAQKAAAFED
Entry containing the structure of the following domain or dimerisation domain
structures with the least restraint violations
Talin c-terminal actin binding site (ABS3)
Final Structures refined in explicit water bath as implemented in Aria 1.2/CNS 1.1. 20 lowest energy structures selected from water refinement., CNS, Initial structures generated with Cyana
simulated annealing, molecular dynamics, torsion angle dynamics
1 mM Talin c-terminal actin binding site (ABS3), 90% H2O/10% D2O
1 mM [U-15N] Talin c-terminal actin binding site (ABS3), 90% H2O/10% D2O
1 mM [U-13C; U-15N] Talin c-terminal actin binding site (ABS3), 90% H2O/10% D2O
Talin, C-terminal actin binding site, ABS3, THATCH domain, Cytoskeleton, Phosphorylation, Structural protein, ACTIN-BINDING PROTEIN
DPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAI PANALDDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAA GNAVKRASDNLVKAAQKAAAFED