Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins
Effect of C-terminal amidation on folding and disulfide-pairing of alpha-conotoxin ImI
Chemically synthesized using Fmoc solid phase peptide synthesis.
Energy Minization, Molecular Dynamics, Simulated Annealing
2mM peptide sample, pH 3.0; 10% D2O, 90% H2O
Conotoxin, disulfide linkage, ribbon conformation, TOXIN