Selenomethionine derivative of griffithsin
Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
GSSHHHHHHSSGLVPRGSLTHRKFGGSGGSPFSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISN (MSE)TIRSGDYIDNISFETN(MSE)GRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
GSSHHHHHHSSGLVPRGSLTHRKFGGSGGSPFSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTI RSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
0.2M ammonium sulfate, 30% PEG 4000, pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
griffithsin, lectins, domain swapping, mannose binding, HIV, SARS, SUGAR BINDING PROTEIN