Solution Structure of alpha-Conotoxin OmIA
Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes
This sequence occurs naturally in Conus omaria.
This structure was determined using standard 2D homonuclear techniques.
4.8mM alpha-conotoxin OmIA; 90% H2O, 10% D2O
alpha-helix, beta-turn, two disulfide bonds, C-terminal amidation, TOXIN