CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE

Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.

Substrate Requirements for Ermc' Methyltransferase Activity

Sequence and Properties of Pim13, a Macrolide-Lincosamide-Streptogramin B Resistance Plasmid from Bacillus Subtilis

MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQV
LNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPR
EYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYK
LFNK

DATA FOR MAD PHASING WAS DONE WITH OTHER EXPERIMENTAL CONDITIONS.

STRUCTURE WAS SOLVED IN P622 SPACE GROUP BUT WAS REFINED IN P6.

METHYLTRANSFERASE, ANTIBIOTIC RESISTANCE, RRNA METHYLTRANSFERASE, ERYTHROMYCIN RESISTANCE METHYLASE C'