Fully automated solution structure determination of the Fes SH2 domain
Automated protein structure determination from NMR spectra
Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes
NMR assignment of the SH2 domain from the human feline sarcoma oncogene FES
Proto-oncogene tyrosine-protein kinase Fes/Fps
GSSGSSGEVQKPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSLDNLYRLEGEGFPS IPLLIDHLLSTQQPLTKKSGVVLHRAVPSGPSSG
NMR structure of the human Fes SH2 domain determined by conventional methods
structures with the least restraint violations
Fully automated NMR spectrum analysis and structure calculation without human intervention. Chemical shift assignments and conformational restraints have not been verified manually.
1.2MM UNIFORMLY 13C AND 15N LABELED PROTEIN; 20MM TRIS-HCL BUFFER; 100MM NACL; 1MM DITHIOTHREITOL; 0.02% NAN3
SH2 domain, Fes, feline sarcoma oncogene, fully automated structure determination, FLYA algorithm, TRANSFERASE