Solution structure of the NRSF/REST-mSin3B PAH1 complex
The Neural Repressor NRSF/REST Binds the PAH1 Domain of the Sin3 Corepressor by Using its Distinct Short Hydrophobic Helix
Sin3 interaction domain (residues 43-57)
Sin3B, Transcriptional corepressor Sin3b, Histone deacetylase complex subunit Sin3b
HELIX DETERMINATION METHOD: AUTHOR DETERMINED
This sequence occurs naturally in humans.
0.5-0.8mM PAH1 U-15N,13C; 0.5-0.8mM SID; 20mM potassium phosphate buffer
NRSF, Sin3, PAH1, transcriptional repressor, GENE REGULATION