Crystal structure of human purple acid phosphatase with an inhibitory conformation of the repression loop

Crystal Structures of Recombinant Human Purple Acid Phosphatase with and without an Inhibitory Conformation of the Repression Loop.

TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5

PURPLE ACID PHOSPHATASE, TR-AP, TRATPASE, TARTRATE-RESISTANT ACID ATPASE

ATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRK
VPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLA
RTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAG
NFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP

0.05 M HEPES PH6.0, 2 M AMMONIUM SULFATE, 10% PEG400, 0.05M ZINC SULFATE, pH 6.00

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.

METALLOPHOSPHATASE, DINUCLEAR METAL SITE, TRAP, HYDROLASE